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Welcome to our guide to The Binding of Isaac: Rebirth Hush Unlocks Rankings. Below you can find the individual rankings.
The Binding of Isaac: Rebirth Hush Unlocks Ranking
Isaac: Farting baby
Difficulty: 6/10
Isaac gets off fairly easy with hush, what with all the free loot to reroll before fighting the man himself.
Unlock rating: C
Not the worst thing to exist, but is outright outclassed by dumpt now and seems to only trigger once a century.
Maggy: Purity
Difficulty: 5/10
Health is something one needs a lot of going into this fight, and that is Maggy’s entire gimmick. -1 point for low starting speed though.
Unlock rating: C
either profoundly useful or profoundly useless, because of course it decided to buff range.
Cain: D12
Difficulty: 6/10
the 4 gold chests pretty much guarantee access to the item rooms, though low starting range and hp make it slightly harder.
Item rating: D
every time i’ve picked up this item, it’s done absolutely nothing to help me. not that it has no uses, just that they’re highly situational.
Judas: Betrayal
Difficulty: 7/10
Book of Belial is decent, but low af starting health makes hush much harder than i’d think.
Item rating: B
ironically, works best against hush, but is also pretty solid against general rooms.
???: Fate’s reward
Difficulty: 8/10
hope and pray that you get soul hearts on hush floor, or else you’re gonna have a bad time.
Item rating: C
if it had actual fire rate, i’d rate it much more. otherwise just a low fire rate incubus
Eve: Athame
Difficulty: 6/10
either sacrifice a lot of damage, or beat hush on soul hearts, pick your poison.
Item rating: A
used to be mid, now it’s outrageously powerful in bursts. broke hush’s boss armor with this before, pretty good.
Samson: Blind rage
Difficulty: 6/10
the fact that the floor is just hush makes bloody lust pretty bad, so basically just D6less Isaac.
Item rating: B
boosted i frames are not to be slept on, though admittedly it is hard to notice quite immediately what it does.
Azazel: Maw of the void
Difficulty: 8/10
range ups are a near requirement. that or an absurd number of damage upgrades.
Item rating: A
low range, but really good damage. used to be flat out overpowered, but is still solid.
Lazarus: Empty vessel
Difficulty: 6/10
extra life makes hush marginally easier, but it’s still no cake walk.
Item rating: D
only really ever does anything for soul heart characters, and even they don’t want to take devil deals.
Eden: Eden’s blessing
Difficulty: 7/10
the general low starting health makes this fight a bit questionable imo, but otherwise just kinda random.
Item rating: B
tears up is solid, but the main thing is that extra starting item. very nice.
The Lost: Sworn protector
Difficulty: 9/10
INTENSE SUFFERING
Item rating: B
an orbital that pulls in projectiles towards itself, and can occasionally spawn eternal hearts is pretty good, but i’m knocking this one down for being in the angel deal pool.
Lilith: Incubus
Difficulty: 7/10
no need to worry about getting blocked by rocks, but Lilith is still pretty annoying to play.
Item rating: S
i feel i don’t have to justify putting this as S tier, i mean, have you seen this thing in action?
The Keeper: Keeper holds a penny
Difficulty: 8/10
pretty difficult coz of the health cap, but there’s absolutely no reason to not be at full health when entering hush.
Unlock rating: D
yeah sure it makes Keeper much easier by giving him a health up, but it does literally nothing for all other characters.
Apollyon: Hushy
Difficulty: 6/10
same thing as Isaac, given they’re practically the same character but with different starting items.
Item rating: D
one of the most inconsequential familiars, even more so than brother bobby and sister maggy, who at least contribute to conjoined!
The Forgotten: Hallowed ground
Difficulty: 5/10
sticking as the soul for most of the fight and using the body as a shield can make this much easier.
Item rating: C
useful for the roughly 5 miliseconds you get in the aura before either enemy projectiles or your own tears break the poop spawned.
Bethany: Divine intervention
Difficulty: 5/10
not too difficult to get through if you have a good deal of whisps, only you won’t have many (if any at all) once you’ve beaten him.
Item rating: A
it reflects lasers, very cool.
Jacob and Esau: Vanishing twin

Difficulty: 9/10
if you start questioning your sanity while trying to get this unlock, don’t worry, that’s natural.
Item rating: B
we could do with more risk/reward items like this. only donwside is its useless past womb 1.